Liver resection as part of secondary cytoreduction in recurrent epithelial ovarian cancer

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Role of secondary cytoreduction in recurrent ovarian cancer

Theoretical background for primary & secondary surgical cytoreduction An estimated 21,550 women are diagnosed with ovarian cancer annually in the USA [1]; it is the leading cause of gynecologic cancer-related deaths, with approximately 14,600 deaths per year. For advanced ovarian cancer, the therapeutic role of primary cytoreductive surgery with the aim of complete resection followed by platinu...

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Feasibility of laparoscopic cytoreduction in patients with localized recurrent epithelial ovarian cancer

OBJECTIVE To assess the feasibility of laparoscopic cytoreduction in patients with localized recurrent epithelial ovarian cancer (EOC) by comparing its outcomes to those of laparotomy. METHODS We performed retrospective analysis in 79 EOC patients who had a localized single recurrent site, as demonstrated by computed tomography (CT) scan, magnetic resonance imaging, or positron emission tomog...

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Tertiary cytoreduction in the setting of recurrent ovarian cancer (Review)

Ovarian cancer is the most lethal gynecological malignancy, with aggressive surgical debulking and adjuvant chemotherapy as the main treatment modalities. Optimal debulking during the primary surgery is significantly correlated with prolonged survival. As surgical techniques and chemotherapeutic agents improve, more patients with prolonged survival may face secondary and tertiary recurrences. T...

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Secondary cytoreduction surgery improves prognosis in platinum-sensitive recurrent ovarian cancer

BACKGROUND There is no consensus regarding the secondary cytoreduction surgery (CRS) in recurrent ovarian cancer patients. The present study aims to determine the value of secondary CRS and the eligible subgroup for this procedure. METHODS 96 platinum-sensitive recurrent ovarian cancer patients were recruited from Jiangsu Institute of Cancer Research between 1992 and 2011. Follow-up was condu...

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Secondary surgical cytoreduction for advanced epithelial ovarian cancer. Patient selection and review of the literature.

BACKGROUND Standard therapy for advanced epithelial ovarian cancer now includes primary cytoreductive surgery followed by combination chemotherapy. Optimal primary debulking is associated with improved clinical response rates to primary chemotherapy as well as longer overall survival. The benefits of secondary cytoreductive surgery for persistent or recurrent ovarian cancer have not been as cle...

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ژورنال

عنوان ژورنال: HPB

سال: 2016

ISSN: 1365-182X

DOI: 10.1016/j.hpb.2016.01.083